The national average of positive mental health is 50.7. Four weeks after a Synthesis retreat, our participants go from 48.6 to 54.5. A tremendous 10% lasting increase.
Synthesis participants report better sleep, decreased rumination on negativity, positive mood, improved concentration, and healthier lifestyle habits including nutrition and exercise.
The degree of connection that each participant experienced to themselves, others, and nature, more than doubled after Synthesis, an increase of 118%. About half of participants expressed having a full mystical experience.
The degree of fear and stress reported by participants decreased by and remained lowered by 13.8%.
Our team of medical professionals perform comprehensive health screenings for all applicants in order to identify any personal health risks, ensuring the safety of all of our participants.
The Synthesis Retreat Team consists of experienced professionals; trained in the best practices used in clinical trials, they have prepared and guided hundreds of participants safely through the full variety of psychedelic experiences.
Through our collaboration with the Psychedelic Research Group at Imperial College London, Synthesis is contributing to pioneering data. Even in healthy individuals, we found a 42.4% sustained reduction in depressive symptoms.
We will guide you through our carefully designed truffles containing psilocybin journey to experience the full potential of psychedelics. Lying down comfortably with your eyes gently covered, we will provide you with the best way to consume the truffles to minimize nausea, letting yourself be guided through an amazing sound experience, knowing you are safe and supported.
In-depth Exploration Call
Individual Health Screening
In committing to this experience, you will be a pioneer in your own right, joining a specially curated list of attendees who are contributing to the next conscious evolution of humanity in a significant way.
Schedule your complimentary Exploration Call where you will speak privately one-to-one with a Synthesis team member. This is your time to dive deeper into your intentions, questions, hopes and potential concerns about the journey ahead.
With your safety as our priority, prior to your call, you complete a health screener form that is reviewed by medical professionals to ensure your safety before, during and after your journey.
During your Exploration Call, you could be invited to attend a retreat and we will discuss the best options to suit your needs including dates and programs.
Prior to your retreat, you will receive all the practical information you need, as well as an invitation to your first group preparation call, where you will have the opportunity to meet and connect with your facilitators and fellow participants.
Our most comprehensive program, Expansion is a complete 7-week program designed for deep transformations. More than just a truffles containing psilocybin ceremony, you will use this window of plasticity to grow your presence, self-acceptance, focus, and expand your range of states of consciousness in your daily life.
Our standard 3-day retreat near Amsterdam in which you experience one moderate-to-high dose of truffles containing psilocybin to catalyze emotional breakthroughs and deepen self-understanding.
Leadership is born from the relationship we have with ourselves; it is not a job title, it is a decision. We believe that true leadership is something that all women can access, with the right tools. During this five-day wellness retreat, made by women for women, you will relax, explore, learn, discover, breathe, heal, recharge and reach a state of alignment with your past, present and future selves, and the world around you.
This unique Synthesis men-only retreat is a rite of passage that will support deep personal exploration of oneself within a strong, safe and mature container. Diving deeply into ‘liminal realms’ and non-ordinary states of consciousness with truffles containing psilocybin, we will explore together what it means fully to be a man who is capable of discernment, protection, heartful relating and embodied leadership.
Synthesis offers private retreats, an opportunity to work with two facilitators privately instead of participating in our larger group retreat model. The private retreat format offers participants the ability to customize their ceremony, tailoring the individual needs to maximize the transformational potential of their experience. Click below to see if this retreat is right for you.
Based in the Netherlands, we offer a 100% legal way to explore your mind with truffles. Access to expanded states of consciousness in a modern, comfortable, medically supervised context.
Synthesis is committed to science-based data and contributing to research. To date we’ve collaborated with The Psychedelic Research Group of Imperial College London in a pilot study where we discovered that the biggest factors for a transformational psychedelic journey are: sense of safety, quality of intention, the absence of escapist behaviours and distractions, and the feeling of community - all important aspects that we safeguard. By attending Synthesis you get the opportunity to contribute to pioneering science and furthering the well-being of our planet.
Your journey begins with an in-depth exploration call to fully understand your background and needs, so we can provide absolute clarity in the journey ahead and how to get the most out of your experience. Throughout the retreat, we cater to your individual needs by offering workshops for all levels and one-on-one consultations with our professionals, in order for you to go in prepared and process your experience to extract valuable life lessons.
The application procedure involves a thorough check by our health team to ensure your safety. Medical practitioners are present during the retreat.
All our programs include a preparation and integration program. Preparation is key for maximising the potential of a beneficial psychedelic experience and integration is important for prolonging the well-being benefits. We are dedicated to ensuring that our participants understand the unique ways that truffles containing psilocybin can aid in healing and growth, the importance of set, setting, intentions, and personal practices.
We designed your whole journey in order to reduce any anxiety or nervousness you might feel. From the sound experience to personalized care, every element is planned to ensure your optimal mindset and comfort in the setting, preparing you for your psychedelic experience with as little resistance as possible.
You will receive lifetime access to our private community as part of your retreat commitment. This ever-evolving community offers access to professional support and networking as you continue the process of your own psychedelic journey and personal development.
Synthesis is pioneering transformative wellness to help you achieve wisdom-lessing, improved connections, lasting betterment in your mood, outlook on life, relationships, and overall mental wellbeing through medically-overseen, guided psychedelic experiences. We use a combination of truffles containing psilocybin, evidence-based wellness programs, and the support of an interdisciplinary team of experienced guides to optimize your healing journey. Read more about us.
Synthesis is for people who are looking for the best in mental health and wellness practices. We work with professionals of all walks of life and ages, from those who are new to expanded states of consciousness, as well as the highly experienced. Read more about who comes to Synthesis.
You begin by scheduling discovery call with your Synthesis guide to see if a truffles retreat is right for you. Before your call, we will ask you some personal and medical data. Then, we’ll book your dates, send you your preparation information, and introduce you to your group and lead facilitator for your retreat. Book your call.
We have scholarships available. Please ask for on your exploration call what is possible for you.
It’s important to know that we do not offer any therapy. While our protocols and trainings are based on the best therapeutic practices currently available in this field, scientific research is still working on what constitutes proper therapy. What we offer is a safe and compassionate space where you can explore your own consciousness with all the beauty and darkness, love and difficulties that reside within it. We adhere to the best professional standards, but do not give treatment nor actively work with depression or traumas at this time.
We're working hard to develop our capacities which will allow us to offer legal therapeutic treatment in the near future. We're happy to keep in touch over email as we fulfill this long-standing ambition.
According to recent studies, psilocybin mushrooms (which have the same active ingredient as truffles) are the safest drug currently known - safer than tobacco, cannabis, and alcohol. These substances are non-addictive, non-toxic, and, when taken within a structured setting under the guidance of medical professionals, hold little to no risk. Read more about truffles.
The active ingredient in truffles is psilocybin.
Psilocybin, upon entering the body, is quickly metabolized into psilocin, which is responsible for the well-known psychedelic effects. Psilocin acts on serotonin at the 5-HT2A receptor, increasing the amount of serotonin available in the brain, and producing profound changes in perception, such as visual and auditory hallucinations, tactile perceptions (such as tingling or warmth), and synaesthesia (the merging of senses).
Users of psilocybin report entering a profound state of mind where the usual limits of consciousness are expanded. Realizations about the self and the universe may come to the forefront, and people will often describe feelings of unity, interconnectedness, and unconditional love. Studies have shown that psilocybin can induce a mystical experience and that this positively correlates with the benefits that users report following the trip.
We determine our dosage together with you during your 1-1 conversation. What we recommend varies, depending on your intentions, previous experience, your sensitivity to expanded states of consciousness, and your anxiety level on retreat. On average we use the clinical standard of 30mg/70kg of psilocybin and psilocin. When it is your first time, we recommend a slightly lower dose to get more comfortable with these states of consciousness. If you have more experience or a strong contemplative practice, we are open to provide much higher dosages.
The simple answer to this question is that we review applications on a case-by-case basis based on both psychological and medical history, as well as current medications, to look for any contraindications before we can formally accept or not accept an applicant.
Our medical team is sometimes able to tell you under which conditions it’s safe for you to come on retreat, for example if you are able to taper off under correct supervision and receive sufficient aftercare after your retreat.
Everyone who we can’t accept at this time gets put into a contact list where we will monitor and reconnect as we expand our capacity to take on more and more people through building up and improving upon our support capabilities - which include therapeutic support pre-retreat and post-retreat. To learn more, read our article ‘Can you take shrooms on antidepressants?’
In any case, you're invited to book an Exploration Call and go through the Health Check.
We would like to make sure you have all your questions answered and trust a Synthesis retreat is right for you. That is why the first step towards joining a retreat is to book an exploration call with us. During this call, we'll explore your intentions, your questions and any concerns you might have. We'll also share more about our programs and explore if we are a good fit.
However, if there is a reason you do wish to attend the call, or would like to make an urgent booking, here is what to do:
Click, BOOK A CALL and follow the process outlined. While you pick your date and time, complete a few questions to help us personalize your experience.
Next, complete the medical screening process, and if approved, you will receive an email from us confirning your call. To bypass the exploration call stage simply reply to that email (or email us directly at firstname.lastname@example.org) and indicate the reason for not attending the call and the dates and program you would like to attend. We will correspond through email with you.
In order for us to accurately assess your suitability and safety for a psilocybin journey, as well as to provide you with a personalized experience during your retreat, we would love to get to know you better first and see whether Synthesis is right for you.
If your screener identifies anything that requires a closer look by our medical team, we will wait until we get clearance from them. In the meantime, we will postpone your Exploration Call while we work with you on your case.
There are three possible outcomes of this review:
We understand this may feel like a roadblock and we want you to know that our medical team will work with you, with your best interests at heart, to determine the best course of action. Thank you for your patience and understanding. Your safety is our primary concern.
Studies have shown that the context of a group retreat and having experienced guides are essential ingredients to properly optimize for safety and getting the most out of a psychedelic experience. From years of retreat experience we know the value of this experience is rooted in the whole process, from being able to surrender fully because there is medical and professional support, to the meaningful relationships you will build with others.
We provide a comfortable indoor space with mattresses to lay down on, eye shades, and profound music. There are also creative spaces inside and outside to explore. In creating an optimal environment for your psychedelic experience, we combine ceremonial aspects rooted in age-old tradition with modern approaches that have proven, in scientific research, to be effective at facilitating a deep, meaningful experience.
Upon arrival, guests participate in both group and individual workshops to help prepare them for the truffles ceremony. On the day of the ceremony, guests participate in a breathwork session and are carefully supported by experienced practitioners, including an on-site medic as they experience truffles in a therapeutic context. After the ceremony, guests participate in group and individual workshops focused on integration before customers return home. Additional preparation and integration support is also offered digitally outside of in-person retreat dates.
Although psychedelic retreats are mostly associated with younger generations, Synthesis participants come from a variety of age groups. Starting at 18 years old, which is the age to be legally eligible for a retreat, we regularly host individuals in the midst of the early, mid, and late stages of life. These distinct stages each come with their own trials and tribulations, something which our retreats and team of experts are equipped to support.
To learn more about the use of psychedelics in mid to late life, read our article Psychedelics and Age.
We keep all personal information confidential, none of it will be shared with third parties.
Yes, we do! Please see our private retreat offer for more details. We also offer 1-to-1 preparation and integration coaching as an option during our group retreats, for an additional fee.
Yes, you can. A second retreat can be a quite different experience, certainly not just a repetition. In case it‘s your second overall psychedelic experience, many people tend to be even better prepared and relaxed as there is a familiarity that allows them to let go or direct their experience even more. For experienced psychonauts on the other hand, each experience can have its own focus or topic, exploring different aspects.
You are welcome to stay an extra night at the venue either pre-retreat, post-retreat or both. We charge an additional cost of $200 for each night.
Please note that because your extended stay is beyond our normal retreat schedule, you will be responsible for your own transportation and your own meals during this time. We will be very happy to assist or point you in the right direction for both. Your apartment’s kitchen is well equipped for cooking and there are many restaurants and grocery stores within a short walk of the venue.
Check in time early arrival: between 12pm and 19:00 / 7:00 PM* Check out time late departure: 10:00 AM
You are welcome to use the sauna and the facilities in your apartment, but the access to the rest of the building will be restricted. The retreat team is preparing for your retreat, and so the common areas like the church and ceremony space are off limits. We appreciate your understanding.
Arrival to Schiphol International Airport: Please keep in mind that you should land by 10.30 AM CEST (local time) at Amsterdam Airport on the first day of your retreat to make it through customs on time. The shuttle service to the venue leaves at 11.30 AM CEST.
We are aware that the time window for arrival might be limited. If you have trouble booking a flight that lands before 11.00AM on the first retreat day, please contact us so we can help you with the travel schedule.
Departure from Schiphol International Airport: We advise to book your returning flight after 19.00pm CEST on the day of departure, as the retreat will wrap up at 16.00pm CEST and drop off will be at Amsterdam Central Station or Schiphol International Airport at 16:30 - 17:00pm. This should give you sufficient time to make it through customs without any unnecessary stress.
Coming together or not is a very personal decision. Many couples join us for a retreat together and have a wonderful time. Coming together can be a very bonding experience for both of you, a transformative experience to share and remember. Our Director of Operations actually came as a participant to one of our first ceremonies with her husband. She often reminisces with a smile that the experience brought them much closer together.
In some cases, it might make sense to come alone. If you have a personal issue you’d like to work on during the retreat, having your significant other around could be a distraction for you. For instance, you might end up worrying about them and be unable to focus on your own process. In this case coming separately might be better.
Have you already decided that you’ll come together? Excellent. This is how it works: Both of you need to sign up for an Exploration Call, which is followed by our Health Check. The Health Check is a mandatory step for each of you. You may schedule your call together or separately, that’s up to you, but please let your exploration guide know in advance if you come together on your call.